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While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control

Glycine Increases Insulin Sensitivity and Glutathione Biosynthesis and Protects against Oxidative Stress in a Model of Sucrose-Induced Insulin Resistance

By reducing oxidative stress, Glutathione can help improve insulin sensitivity

It is a good idea to choose suitable positions along the helical peptide for the placement of staples

Nature 616 , 790797 (2023)

Jill Carnahan, MD Agreed